CMap Candidate Details

Structure:
CMap ID: C00647
Pert ID: BRD-A25687296
Compound Name: emetine
Targets: RPS2
MoA: Protein synthesis inhibitor
SMILES: CC[C@H]1CN2CCc3cc(OC)c(OC)cc3C2C[C@@H]1CC1NCCc2cc(OC)c(OC)cc12
InchiKey: AUVVAXYIELKVAI-VXNUJMKFSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
5391 BRD-A25687296 HA1E 10 uM 6 h 0.28 1.15 0.34 0.0 0.0 0.0
5716 BRD-A25687296 HCC515 10 uM 6 h 0.33 1.38 0.97 -0.5 -1.68 15.65
5832 BRD-A25687296 HEPG2 10 uM 6 h 0.0 0.0 0.0 -0.39 -1.3 1.58
5976 BRD-A25687296 HT29 10 uM 6 h 0.29 1.21 0.45 -0.44 -1.48 15.35
6066 BRD-A25687296 MCF??7.00 10 uM 6 h 0.32 1.32 0.83 -0.37 -1.26 1.35
41655 BRD-A25687296 A375 10 uM 6 h 0.34 1.42 1.08 -0.52 -1.76 15.65
41875 BRD-A25687296 A549 10 uM 24 h 0.0 0.0 0.0 -0.45 -1.51 15.35
42189 BRD-A25687296 ASC 10 uM 24 h 0.3 1.25 0.54 -0.28 -0.96 0.42
43389 BRD-A25687296 NPC 10 uM 24 h 0.0 0.0 0.0 -0.33 -1.12 0.94
44001 BRD-A25687296 SKB 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
95999 BRD-A25687296 PHH 3.33 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
96287 BRD-A25687296 U2OS 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
96557 BRD-A25687296 PC3 3.33 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).