CMap Candidate Details

Structure:
CMap ID: C06471
Pert ID: BRD-K13044802
Compound Name: ciclopirox
Targets: ATP1A1
MoA: Membrane integrity inhibitor
SMILES: Cc1cc(C2CCCCC2)n(O)c(=O)c1
InchiKey: SCKYRAXSEDYPSA-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
51698 BRD-K13044802 MCF??7.00 10 uM 6 h 0.0 0.0 0.0 -0.27 -0.89 0.27
115979 BRD-K13044802 A375 3.33 uM 24 h 0.0 0.0 0.0 -0.32 -1.08 0.79
116020 BRD-K13044802 A549 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
116059 BRD-K13044802 HA1E 3.33 uM 24 h 0.0 0.0 0.0 -0.28 -0.95 0.39
116101 BRD-K13044802 HCC515 3.33 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
116146 BRD-K13044802 HEPG2 3.33 uM 24 h 0.0 0.0 0.0 -0.36 -1.22 1.24
116192 BRD-K13044802 HT29 3.33 uM 24 h 0.0 0.0 0.0 -0.27 -0.91 0.31
116269 BRD-K13044802 PC3 3.33 uM 24 h -0.24 -1.0 0.14 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).