CMap Candidate Details

Structure:
CMap ID: C06521
Pert ID: BRD-K13169950
Compound Name: NSC-3852
Targets: HDAC1
MoA: HDAC inhibitor
SMILES: Oc1ccc([N+][O-])c2cccnc12
InchiKey: RZWRYPGAUIOOMK-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
4063 BRD-K13169950 HA1E 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
4549 BRD-K13169950 HCC515 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
4650 BRD-K13169950 PC3 10 uM 24 h 0.19 0.8 0.0 0.0 0.0 0.0
4896 BRD-K13169950 VCAP 10 uM 24 h 0.0 0.0 0.0 -0.39 -1.31 1.71
44307 BRD-K13169950 A375 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
44522 BRD-K13169950 A549 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
44861 BRD-K13169950 ASC 10 uM 24 h 0.19 0.81 0.0 -0.29 -0.97 0.46
45166 BRD-K13169950 HEPG2 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
45433 BRD-K13169950 HT29 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
45775 BRD-K13169950 MCF??7.00 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
46296 BRD-K13169950 PHH 10 uM 24 h -0.25 -1.04 0.21 -0.3 -1.01 0.57
46611 BRD-K13169950 SKB 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
98794 BRD-K13169950 NPC 10 uM 6 h 0.0 0.0 0.0 0.26 0.9 0.23
99004 BRD-K13169950 NEU 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
100102 BRD-K13169950 U2OS 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).