CMap Candidate Details

Structure:
CMap ID: C06537
Pert ID: BRD-K13211965
Compound Name: L-741742
Targets: DRD4
MoA: Dopamine receptor antagonist
SMILES: Cc1c(noc1-c1ccc(Cl)cc1)C1CCN(CCc2ccccc2)CC1
InchiKey: QDMAKDIDFJTXEL-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
6867 BRD-K13211965 A375 10 uM 6 h 0.0 0.0 0.0 -0.21 -0.7 0.03
6975 BRD-K13211965 A549 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
7295 BRD-K13211965 HA1E 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
7625 BRD-K13211965 HCC515 10 uM 6 h -0.23 -0.95 0.09 0.0 0.0 0.0
7836 BRD-K13211965 HT29 10 uM 24 h 0.17 0.71 0.0 0.0 0.0 0.0
8078 BRD-K13211965 MCF??7.00 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
8349 BRD-K13211965 PC3 10 uM 24 h -0.25 -1.03 0.19 0.25 0.87 0.17
8802 BRD-K13211965 VCAP 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
100103 BRD-K13211965 U2OS 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).