CMap Candidate Details

Structure:
CMap ID: C06564
Pert ID: BRD-K13296708
Compound Name: rimonabant
Targets: CNR1
MoA: Cannabinoid receptor antagonist
SMILES: Cc1c(nn(c1-c1ccc(Cl)cc1)-c1ccc(Cl)cc1Cl)C(=O)NN1CCCCC1
InchiKey: JZCPYUJPEARBJL-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
98577 BRD-K13296708 NEU 10 uM 6 h 0.27 1.12 0.27 0.0 0.0 0.0
98674 BRD-K13296708 NPC 10 uM 6 h 0.0 0.0 0.0 -0.32 -1.08 0.8
122252 BRD-K13296708 A375 1.11 uM 24 h 0.0 0.0 0.0 -0.28 -0.94 0.37
122315 BRD-K13296708 HEK293 3.33 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
122330 BRD-K13296708 HELA 10 uM 24 h 0.0 0.0 0.0 -0.25 -0.85 0.2
122362 BRD-K13296708 MCF10A 0.125 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
122389 BRD-K13296708 MCF??7.00 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
122440 BRD-K13296708 PC3 10 uM 24 h -0.27 -1.11 0.36 0.45 1.6 2.37
122475 BRD-K13296708 THP1 10 uM 24 h 0.0 0.0 0.0 0.28 0.98 0.37
130555 BRD-K13296708 A549 0.74 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
130590 BRD-K13296708 HA1E 0.74 uM 24 h -0.2 -0.82 0.0 0.0 0.0 0.0
130707 BRD-K13296708 HT29 2.22 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
130783 BRD-K13296708 MDAMB231 0.01 uM 24 h 0.26 1.08 0.21 0.0 0.0 0.0
130836 BRD-K13296708 YAPC 0.01 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).