CMap Candidate Details

Structure:
CMap ID: C00659
Pert ID: BRD-A26095496
Compound Name: clobetasol
Targets: NR3C1
MoA: Glucocorticoid receptor agonist
SMILES: CCC(=O)O[C@@]1([C@@H](C)CC2C3CCC4=CC(=O)C=C[C@]4(C)[C@@]3(F)[C@@H](O)C[C@@]21C)C(=O)CCl
InchiKey: CBGUOGMQLZIXBE-BHPVMOEKSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
5717 BRD-A26095496 HCC515 10 uM 6 h 0.0 0.0 0.0 -0.4 -1.35 2.01
6363 BRD-A26095496 VCAP 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
37054 BRD-A26095496 A375 10 uM 6 h 0.2 0.84 0.0 0.0 0.0 0.0
37464 BRD-A26095496 ASC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
37798 BRD-A26095496 HEPG2 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
38314 BRD-A26095496 NPC 10 uM 24 h -0.23 -0.95 0.09 -0.29 -0.97 0.46
38614 BRD-A26095496 PHH 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
38837 BRD-A26095496 SKB 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
119973 BRD-A26095496 A549 10 uM 24 h 0.0 0.0 0.0 -0.36 -1.23 1.25
120017 BRD-A26095496 HA1E 10 uM 24 h 0.0 0.0 0.0 -0.31 -1.05 0.7
120042 BRD-A26095496 HELA 0.37 uM 24 h 0.0 0.0 0.0 -0.37 -1.26 1.38
120089 BRD-A26095496 HT29 3.33 uM 24 h 0.17 0.7 0.0 0.0 0.0 0.0
120134 BRD-A26095496 MCF??7.00 3.33 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
120175 BRD-A26095496 PC3 0.04 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
120207 BRD-A26095496 YAPC 10 uM 24 h 0.0 0.0 0.0 -0.28 -0.93 0.35
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).