CMap Candidate Details

Structure:
CMap ID: C00663
Pert ID: BRD-A26199074
Compound Name: calmidazolium
Targets: ATP2B1; PDE1A
MoA: Calmodulin antagonist; Calcium channel blocker
SMILES: Clc1ccc(cc1)C(c2ccc(Cl)cc2)n3cc[n+](CC(OCc4ccc(Cl)cc4Cl)c5ccc(Cl)cc5Cl)c3
InchiKey: CTKNMSVWMRRCPW-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
33878 BRD-A26199074 A549 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
33981 BRD-A26199074 ASC 10 uM 24 h 0.22 0.92 0.04 -0.31 -1.03 0.63
34495 BRD-A26199074 HCC515 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
34766 BRD-A26199074 HEPG2 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
35042 BRD-A26199074 HT29 10 uM 6 h 0.0 0.0 0.0 -0.38 -1.29 1.53
35268 BRD-A26199074 MCF??7.00 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
35506 BRD-A26199074 NEU 10 uM 24 h 0.2 0.84 0.0 0.0 0.0 0.0
35675 BRD-A26199074 NPC 10 uM 24 h 0.0 0.0 0.0 -0.36 -1.22 1.25
36041 BRD-A26199074 PC3 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
36139 BRD-A26199074 PHH 10 uM 24 h 0.0 0.0 0.0 -0.36 -1.2 1.17
36729 BRD-A26199074 VCAP 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).