CMap Candidate Details

Structure:
CMap ID: C00669
Pert ID: BRD-A26384407
Compound Name: chlortalidone
Targets: --
MoA: --
SMILES: NS(=O)(=O)c1cc(ccc1Cl)C1(O)NC(=O)c2ccccc12
InchiKey: JIVPVXMEBJLZRO-UHFFFAOYSA-N
Compound Aliases: chlorthalidone

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
5259 BRD-A26384407 HA1E 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
5718 BRD-A26384407 HCC515 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
20831 BRD-A26384407 MCF??7.00 10 uM 24 h -0.23 -0.96 0.1 0.0 0.0 0.0
21678 BRD-A26384407 VCAP 10 uM 6 h 0.0 0.0 0.0 0.23 0.82 0.1
42190 BRD-A26384407 ASC 10 uM 24 h 0.0 0.0 0.0 -0.27 -0.89 0.27
42534 BRD-A26384407 HEPG2 10 uM 6 h 0.0 0.0 0.0 -0.31 -1.05 0.69
43390 BRD-A26384407 NPC 10 uM 24 h 0.0 0.0 0.0 -0.23 -0.77 0.09
43704 BRD-A26384407 PHH 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
120876 BRD-A26384407 A375 0.37 uM 24 h -0.21 -0.86 0.01 0.0 0.0 0.0
120975 BRD-A26384407 HEK293 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
121132 BRD-A26384407 YAPC 0.125 uM 24 h 0.0 0.0 0.0 -0.3 -1.02 0.59
129123 BRD-A26384407 A549 0.25 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
129173 BRD-A26384407 HELA 0.74 uM 3 h 0.0 0.0 0.0 0.0 0.0 0.0
129205 BRD-A26384407 HT29 0.25 uM 24 h 0.0 0.0 0.0 -0.35 -1.18 1.14
129234 BRD-A26384407 PC3 2.22 uM 24 h 0.29 1.2 0.43 0.21 0.75 0.04
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).