CMap Candidate Details

Structure:
CMap ID: C06717
Pert ID: BRD-K13800121
Compound Name: parecoxib
Targets: LTF; PTGS2
MoA: Cyclooxygenase inhibitor
SMILES: CCC(=O)NS(=O)(=O)c1ccc(cc1)-c1c(C)onc1-c1ccccc1
InchiKey: TZRHLKRLEZJVIJ-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
24411 BRD-K13800121 A375 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
24557 BRD-K13800121 A549 10 uM 24 h 0.0 0.0 0.0 -0.23 -0.77 0.08
24873 BRD-K13800121 HT29 10 uM 6 h -0.18 -0.76 0.0 0.0 0.0 0.0
25085 BRD-K13800121 MCF??7.00 10 uM 6 h -0.19 -0.8 0.0 0.0 0.0 0.0
25144 BRD-K13800121 PC3 10 uM 24 h 0.0 0.0 0.0 0.2 0.7 0.02
25330 BRD-K13800121 VCAP 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).