CMap Candidate Details

Structure:
CMap ID: C00676
Pert ID: BRD-A26690767
Compound Name: saquinavir
Targets: --
MoA: --
SMILES: CC(C)(C)NC(=O)[C@@H]1CC2CCCCC2CN1C[C@@H](O)[C@H](Cc1ccccc1)NC(=O)[C@H](CC(N)=O)NC(=O)c1ccc2ccccc2n1
InchiKey: QWAXKHKRTORLEM-LINFGICFSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
97140 BRD-A26690767 A375 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
97207 BRD-A26690767 PC3 10 uM 24 h 0.19 0.79 0.0 0.0 0.0 0.0
119975 BRD-A26690767 A549 10 uM 24 h -0.22 -0.93 0.07 0.0 0.0 0.0
120045 BRD-A26690767 HELA 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
120092 BRD-A26690767 HT29 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
120136 BRD-A26690767 MCF??7.00 0.04 uM 24 h 0.25 1.05 0.17 0.28 0.98 0.37
128805 BRD-A26690767 HA1E 2.22 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
128862 BRD-A26690767 YAPC 0.74 uM 24 h 0.0 0.0 0.0 0.22 0.77 0.06
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).