CMap Candidate Details

Structure:
CMap ID: C06836
Pert ID: BRD-K14200658
Compound Name: syrosingopine
Targets: --
MoA: --
SMILES: CCOC(=O)Oc1c(OC)cc(cc1OC)C(=O)O[C@@H]2C[C@@H]3CN4CCc5c([nH]c6cc(OC)ccc56)[C@H]4C[C@@H]3[C@@H]([C@H]2OC)C(=O)OC
InchiKey: ZCDNRPPFBQDQHR-SSYATKPKSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
1554 BRD-K14200658 HA1E 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
2085 BRD-K14200658 HCC515 10 uM 6 h 0.0 0.0 0.0 -0.21 -0.72 0.04
2377 BRD-K14200658 PC3 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
2758 BRD-K14200658 VCAP 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
41731 BRD-K14200658 A375 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
42065 BRD-K14200658 A549 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
42306 BRD-K14200658 ASC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
42637 BRD-K14200658 HEPG2 10 uM 6 h -0.2 -0.85 0.01 -0.26 -0.89 0.27
42941 BRD-K14200658 HT29 10 uM 6 h 0.0 0.0 0.0 0.36 1.28 1.37
43297 BRD-K14200658 MCF??7.00 10 uM 6 h 0.0 0.0 0.0 -0.24 -0.82 0.15
43498 BRD-K14200658 NPC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
43800 BRD-K14200658 PHH 10 uM 24 h 0.26 1.08 0.21 -0.27 -0.9 0.29
100112 BRD-K14200658 U2OS 3.33 uM 6 h 0.0 0.0 0.0 0.33 1.17 0.93
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).