CMap Candidate Details

Structure:
CMap ID: C06839
Pert ID: BRD-K14204120
Compound Name: ranitidine
Targets: HRH2
MoA: Histamine receptor antagonist
SMILES: CNC(NCCSCc1ccc(CN(C)C)o1)=C[N+]([O-])=O
InchiKey: VMXUWOKSQNHOCA-LCYFTJDESA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
4064 BRD-K14204120 HA1E 10 uM 24 h 0.22 0.91 0.03 0.27 0.95 0.31
4368 BRD-K14204120 HCC515 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
4779 BRD-K14204120 PC3 10 uM 6 h 0.24 0.99 0.1 0.18 0.65 0.01
5038 BRD-K14204120 VCAP 10 uM 6 h 0.0 0.0 0.0 0.36 1.27 1.34
37367 BRD-K14204120 A549 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
37600 BRD-K14204120 ASC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
37875 BRD-K14204120 HEPG2 10 uM 6 h 0.0 0.0 0.0 -0.24 -0.82 0.15
38057 BRD-K14204120 HT29 10 uM 6 h -0.29 -1.2 0.55 0.39 1.4 2.18
38184 BRD-K14204120 MCF??7.00 10 uM 24 h 0.0 0.0 0.0 0.33 1.19 1.01
38433 BRD-K14204120 NPC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
90980 BRD-K14204120 HUH7 10 uM 72 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).