CMap Candidate Details

Structure:
CMap ID: C06852
Pert ID: BRD-K14221570
Compound Name: benzopurpurin-4b
Targets: --
MoA: --
SMILES: Cc1cc(ccc1N=Nc2cc(c3ccccc3c2N)S(=O)(=O)O)c4ccc(N=Nc5cc(c6ccccc6c5N)S(=O)(=O)O)c(C)c4
InchiKey: PYPYDHUIORYEHW-UHFFFAOYSA-N
Compound Aliases: BENZOPURPURIN-4B

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
5433 BRD-K14221570 HA1E 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
5582 BRD-K14221570 HCC515 10 uM 24 h -0.24 -0.99 0.13 0.0 0.0 0.0
6083 BRD-K14221570 MCF??7.00 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
6263 BRD-K14221570 PC3 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
6523 BRD-K14221570 VCAP 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
37126 BRD-K14221570 A375 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
37368 BRD-K14221570 A549 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
37601 BRD-K14221570 ASC 10 uM 24 h 0.21 0.86 0.01 0.0 0.0 0.0
37876 BRD-K14221570 HEPG2 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
38058 BRD-K14221570 HT29 10 uM 6 h 0.0 0.0 0.0 -0.27 -0.92 0.33
38434 BRD-K14221570 NPC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
38692 BRD-K14221570 PHH 10 uM 24 h 0.0 0.0 0.0 0.21 0.75 0.04
100113 BRD-K14221570 U2OS 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).