CMap Candidate Details

Structure:
CMap ID: C00691
Pert ID: BRD-A27489425
Compound Name: rolitetracycline
Targets: --
MoA: --
SMILES: CN(C)[C@H]1C2CC3C(C(=O)c4c(O)cccc4[C@@]3(C)O)C(=O)[C@]2(O)C(=O)C(C(=O)NCN5CCCC5)C1=O
InchiKey: PLDZOHPIBZVDLQ-ASDJQBJJSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
22090 BRD-A27489425 A375 10 uM 6 h 0.0 0.0 0.0 0.3 1.06 0.58
22094 BRD-A27489425 A549 10 uM 24 h 0.0 0.0 0.0 -0.41 -1.36 2.02
22640 BRD-A27489425 HCC515 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
22921 BRD-A27489425 HEPG2 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
23227 BRD-A27489425 HT29 10 uM 6 h 0.0 0.0 0.0 -0.28 -0.95 0.4
23675 BRD-A27489425 MCF??7.00 10 uM 6 h 0.0 0.0 0.0 0.31 1.09 0.67
23939 BRD-A27489425 PC3 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
24259 BRD-A27489425 VCAP 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).