CMap Candidate Details

Structure:
CMap ID: C06969
Pert ID: BRD-K14529030
Compound Name: meisoindigo
Targets: STAT3
MoA: STAT inhibitor
SMILES: CN1C(=O)C(c2ccccc12)=C1C(=O)Nc2ccccc12
InchiKey: QNOCRUSVMMAKSC-CCEZHUSRSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
122259 BRD-K14529030 A375 0.125 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
122300 BRD-K14529030 HA1E 3.33 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
122320 BRD-K14529030 HEK293 0.125 uM 24 h 0.0 0.0 0.0 -0.48 -1.62 15.65
122393 BRD-K14529030 MCF??7.00 0.125 uM 24 h 0.0 0.0 0.0 -0.24 -0.8 0.11
122482 BRD-K14529030 THP1 10 uM 24 h -0.24 -1.01 0.17 -0.22 -0.73 0.05
130562 BRD-K14529030 A549 0.25 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
130674 BRD-K14529030 HELA 2.22 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
130714 BRD-K14529030 HT29 2.22 uM 24 h 0.22 0.93 0.05 0.0 0.0 0.0
130744 BRD-K14529030 MCF10A 2.22 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
130788 BRD-K14529030 MDAMB231 0.03 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
130816 BRD-K14529030 PC3 2.22 uM 24 h 0.31 1.31 0.75 0.0 0.0 0.0
130841 BRD-K14529030 YAPC 2.22 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).