CMap Candidate Details

Structure:
CMap ID: C07013
Pert ID: BRD-K14681867
Compound Name: somatostatin
Targets: SSTR1; SSTR2; SSTR3; SSTR4; SSTR5
MoA: Somatostatin receptor agonist
SMILES: C[C@@H](O)[C@@H]1NC(=O)[C@H](CCCCN)NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CSSC[C@H](NC(=O)[C@H](CO)NC(=O)[C@@H](NC(=O)[C@H](Cc2ccccc2)NC1=O)[C@@H](C)O)C(O)=O)NC(=O)CNC(=O)[C@H](C)N
InchiKey: NHXLMOGPVYXJNR-ATOGVRKGSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
33670 BRD-K14681867 A375 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
34051 BRD-K14681867 ASC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
34320 BRD-K14681867 HA1E 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
35100 BRD-K14681867 HT29 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
35298 BRD-K14681867 MCF??7.00 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
35544 BRD-K14681867 NEU 10 uM 24 h 0.2 0.83 0.0 -0.44 -1.47 15.35
35736 BRD-K14681867 NPC 10 uM 24 h 0.29 1.2 0.42 -0.22 -0.74 0.05
35937 BRD-K14681867 PC3 10 uM 24 h -0.18 -0.77 0.0 -0.29 -0.97 0.45
36209 BRD-K14681867 PHH 10 uM 24 h 0.0 0.0 0.0 -0.44 -1.47 15.35
36504 BRD-K14681867 SKB 10 uM 24 h 0.0 0.0 0.0 -0.35 -1.19 1.16
36781 BRD-K14681867 VCAP 10 uM 24 h 0.0 0.0 0.0 -0.26 -0.86 0.22
96116 BRD-K14681867 A549 10 uM 24 h -0.29 -1.21 0.57 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).