CMap Candidate Details

Structure:
CMap ID: C07050
Pert ID: BRD-K14790374
Compound Name: BRD-K14790374
Targets: --
MoA: --
SMILES: COc1ccc(C#Cc2ccc3NC(=O)[C@@]4([C@H]([C@H]5N([C@H]4c6ccc(OCCO)cc6)[C@@H]([C@@H](OC5=O)c7ccccc7)c8ccccc8)C(=O)N9CCc%10cc(OC)c(OC)cc%10C9)c3c2)cc1
InchiKey: RKZHAKBSCCRTSX-RXUISWLBSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
25620 BRD-K14790374 A375 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
26079 BRD-K14790374 A549 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
26278 BRD-K14790374 ASC 10 uM 24 h 0.0 0.0 0.0 -0.32 -1.07 0.76
26615 BRD-K14790374 HA1E 10 uM 6 h 0.24 0.99 0.1 0.29 1.04 0.55
26927 BRD-K14790374 HCC515 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
27238 BRD-K14790374 HT29 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
27514 BRD-K14790374 MCF??7.00 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
27861 BRD-K14790374 NEU 10 uM 24 h -0.22 -0.9 0.04 -0.38 -1.28 1.45
28170 BRD-K14790374 NPC 10 uM 24 h -0.31 -1.3 0.81 0.0 0.0 0.0
28452 BRD-K14790374 PC3 10 uM 24 h 0.0 0.0 0.0 -0.3 -1.0 0.52
28811 BRD-K14790374 PHH 10 uM 24 h 0.25 1.05 0.17 0.0 0.0 0.0
29129 BRD-K14790374 SKB 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
29433 BRD-K14790374 VCAP 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).