CMap Candidate Details

Structure:
CMap ID: C07051
Pert ID: BRD-K14791739
Compound Name: fluticasone
Targets: NR3C1; PGR
MoA: Glucocorticoid receptor agonist
SMILES: CCC(=O)O[C@]1([C@H](C)C[C@@H]2[C@H]3C[C@H](F)C4=CC(=O)C=C[C@@]4(C)[C@]3(F)[C@@H](O)C[C@@]12C)C(=O)SCF
InchiKey: WMWTYOKRWGGJOA-GFDKJMNNSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
29791 BRD-K14791739 A375 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
30168 BRD-K14791739 A549 10 uM 6 h 0.0 0.0 0.0 -0.24 -0.82 0.15
30372 BRD-K14791739 ASC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
30692 BRD-K14791739 HA1E 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
30975 BRD-K14791739 HCC515 10 uM 6 h -0.26 -1.1 0.35 -0.33 -1.13 0.98
31278 BRD-K14791739 HEPG2 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
31505 BRD-K14791739 HT29 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
31998 BRD-K14791739 MCF??7.00 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
32739 BRD-K14791739 PC3 10 uM 6 h 0.0 0.0 0.0 -0.23 -0.78 0.1
32954 BRD-K14791739 SKB 10 uM 24 h 0.0 0.0 0.0 0.36 1.27 1.34
33434 BRD-K14791739 VCAP 10 uM 6 h 0.0 0.0 0.0 -0.27 -0.92 0.33
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).