CMap Candidate Details

Structure:
CMap ID: C00708
Pert ID: BRD-A28467416
Compound Name: PKI-179
Targets: MTOR
MoA: MTOR inhibitor; PI3K inhibitor
SMILES: O=C(Nc1ccncc1)Nc1ccc(cc1)-c1nc(nc(n1)N1CCOCC1)N1C2CCC1COC2
InchiKey: WXUUCRLKXQMWRY-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
119985 BRD-A28467416 A549 0.125 uM 24 h 0.23 0.96 0.07 -0.28 -0.93 0.35
120071 BRD-A28467416 HELA 10 uM 3 h 0.0 0.0 0.0 0.0 0.0 0.0
120101 BRD-A28467416 HT29 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
120144 BRD-A28467416 MCF??7.00 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
120183 BRD-A28467416 PC3 0.37 uM 24 h 0.0 0.0 0.0 -0.28 -0.94 0.38
120215 BRD-A28467416 YAPC 0.37 uM 24 h 0.28 1.16 0.34 -0.22 -0.73 0.05
128794 BRD-A28467416 A375 2.22 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
128811 BRD-A28467416 HA1E 2.22 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).