CMap Candidate Details

Structure:
CMap ID: C07083
Pert ID: BRD-K14880289
Compound Name: GW-501516
Targets: PPARD
MoA: Insulin sensitizer; PPAR receptor agonist
SMILES: Cc1nc(sc1CSc1ccc(OCC(O)=O)c(C)c1)-c1ccc(cc1)C(F)(F)F
InchiKey: YDBLKRPLXZNVNB-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
1212 BRD-K14880289 PC3 10 uM 24 h 0.0 0.0 0.0 0.36 1.29 1.49
1254 BRD-K14880289 A549 10 uM 48 h 0.0 0.0 0.0 -0.35 -1.18 1.14
1359 BRD-K14880289 U2OS 0.12 uM 48 h 0.21 0.88 0.01 0.0 0.0 0.0
33731 BRD-K14880289 A375 10 uM 6 h 0.0 0.0 0.0 -0.27 -0.89 0.27
34052 BRD-K14880289 ASC 10 uM 24 h 0.21 0.87 0.01 -0.29 -0.96 0.44
34321 BRD-K14880289 HA1E 10 uM 6 h 0.21 0.89 0.02 0.0 0.0 0.0
34567 BRD-K14880289 HCC515 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
34836 BRD-K14880289 HEPG2 10 uM 6 h 0.0 0.0 0.0 -0.41 -1.37 2.02
35101 BRD-K14880289 HT29 10 uM 6 h -0.21 -0.88 0.03 0.0 0.0 0.0
35495 BRD-K14880289 MCF??7.00 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
35545 BRD-K14880289 NEU 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
35737 BRD-K14880289 NPC 10 uM 24 h 0.0 0.0 0.0 -0.33 -1.1 0.88
36210 BRD-K14880289 PHH 10 uM 24 h 0.0 0.0 0.0 0.32 1.12 0.77
36505 BRD-K14880289 SKB 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
36782 BRD-K14880289 VCAP 10 uM 24 h 0.16 0.67 0.0 -0.17 -0.58 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).