CMap Candidate Details

Structure:
CMap ID: C07086
Pert ID: BRD-K14888893
Compound Name: minoxidil
Targets: ABCC9; KCNJ8; KCNJ11
MoA: Vasodilator; KATP activator; Potassium channel activator
SMILES: Nc1cc(nc(N)[n+]1[O-])N2CCCCC2
InchiKey: ZFMITUMMTDLWHR-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
8916 BRD-K14888893 A375 10 uM 24 h 0.0 0.0 0.0 -0.25 -0.84 0.18
9087 BRD-K14888893 A549 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
9677 BRD-K14888893 H1299 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
10232 BRD-K14888893 HCC515 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
10741 BRD-K14888893 HEPG2 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
10951 BRD-K14888893 HT29 10 uM 24 h 0.0 0.0 0.0 -0.29 -0.99 0.5
11229 BRD-K14888893 MCF??7.00 10 uM 24 h 0.19 0.77 0.0 0.26 0.93 0.26
11429 BRD-K14888893 NCIH2073 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
11721 BRD-K14888893 NCIH508 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
11996 BRD-K14888893 NCIH596 10 uM 6 h 0.0 0.0 0.0 -0.23 -0.78 0.09
12275 BRD-K14888893 NOMO1 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
12556 BRD-K14888893 PC3 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
12741 BRD-K14888893 SW480 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
13089 BRD-K14888893 THP1 10 uM 6 h 0.24 1.0 0.11 0.33 1.18 1.0
13220 BRD-K14888893 U937 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
13451 BRD-K14888893 VCAP 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
50160 BRD-K14888893 HA1E 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
91107 BRD-K14888893 HUH7 15 uM 72 h 0.0 0.0 0.0 0.22 0.78 0.07
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).