CMap Candidate Details

Structure:
CMap ID: C00709
Pert ID: BRD-A28545468
Compound Name: selegiline
Targets: MAOA; MAOB
MoA: Monoamine oxidase inhibitor
SMILES: CC(Cc1ccccc1)N(C)CC#C
InchiKey: MEZLKOACVSPNER-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
90924 BRD-A28545468 HUH7 20 uM 72 h 0.0 0.0 0.0 -0.43 -1.44 15.35
119986 BRD-A28545468 A549 0.04 uM 24 h 0.0 0.0 0.0 -0.38 -1.27 1.39
120102 BRD-A28545468 HT29 1.11 uM 24 h 0.0 0.0 0.0 -0.32 -1.08 0.78
120145 BRD-A28545468 MCF??7.00 0.04 uM 24 h -0.24 -0.98 0.13 0.0 0.0 0.0
128795 BRD-A28545468 A375 0.25 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
128812 BRD-A28545468 HA1E 0.25 uM 24 h 0.0 0.0 0.0 -0.32 -1.09 0.82
128836 BRD-A28545468 HELA 0.74 uM 3 h 0.0 0.0 0.0 0.0 0.0 0.0
128847 BRD-A28545468 PC3 0.74 uM 24 h 0.0 0.0 0.0 -0.3 -1.02 0.6
128869 BRD-A28545468 YAPC 0.25 uM 24 h 0.0 0.0 0.0 -0.25 -0.85 0.19
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).