CMap Candidate Details

Structure:
CMap ID: C07133
Pert ID: BRD-K15086322
Compound Name: JNJ-10191584
Targets: HRH4
MoA: Histamine receptor antagonist
SMILES: CN1CCN(CC1)C(=O)c1nc2ccc(Cl)cc2[nH]1
InchiKey: MOIWSUQWIOVGRH-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
1557 BRD-K15086322 HA1E 10 uM 24 h -0.18 -0.76 0.0 -0.33 -1.1 0.86
2087 BRD-K15086322 HCC515 10 uM 6 h 0.0 0.0 0.0 0.24 0.86 0.16
2378 BRD-K15086322 PC3 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
2708 BRD-K15086322 VCAP 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
41735 BRD-K15086322 A375 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
42069 BRD-K15086322 A549 10 uM 6 h -0.28 -1.17 0.48 0.0 0.0 0.0
42311 BRD-K15086322 ASC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
42642 BRD-K15086322 HEPG2 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
42946 BRD-K15086322 HT29 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
43300 BRD-K15086322 MCF??7.00 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
43502 BRD-K15086322 NPC 10 uM 24 h 0.25 1.02 0.13 -0.26 -0.88 0.26
43802 BRD-K15086322 PHH 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
44079 BRD-K15086322 SKB 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).