CMap Candidate Details

Structure:
CMap ID: C07138
Pert ID: BRD-K15107389
Compound Name: BRD-K15107389
Targets: RPS6KA1; RPS6KA2; RPS6KA3
MoA: Ribosomal protein inhibitor
SMILES: O=C1c2ccccc2-c3c(NCCc4ccccc4)c(=O)[nH]c5cccc1c35
InchiKey: XASCINRGTHLHGM-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
29792 BRD-K15107389 A375 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
30373 BRD-K15107389 ASC 10 uM 24 h 0.0 0.0 0.0 -0.26 -0.89 0.26
30693 BRD-K15107389 HA1E 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
30976 BRD-K15107389 HCC515 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
31279 BRD-K15107389 HEPG2 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
31744 BRD-K15107389 HT29 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
31840 BRD-K15107389 MCF??7.00 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
32363 BRD-K15107389 NPC 10 uM 24 h 0.0 0.0 0.0 0.24 0.86 0.16
32612 BRD-K15107389 PC3 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
32955 BRD-K15107389 SKB 10 uM 24 h -0.28 -1.15 0.44 -0.22 -0.74 0.05
33435 BRD-K15107389 VCAP 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
96192 BRD-K15107389 A549 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
96259 BRD-K15107389 U2OS 10 uM 24 h -0.24 -1.02 0.17 -0.35 -1.19 1.15
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).