CMap Candidate Details
Structure:
| CMap ID: | C07162 |
| Pert ID: | BRD-K15179513 |
| Compound Name: | NVP-ADW742 |
| Targets: | IGF1R |
| MoA: | IGF-1 inhibitor |
| SMILES: | Nc1ncnc2n(cc(-c3cccc(OCc4ccccc4)c3)c12)[C@H]1C[C@H](CN2CCCC2)C1 |
| InchiKey: | LSFLAQVDISHMNB-AFARHQOCSA-N |
| Compound Aliases: | -- |
| Score ID | Pert ID | Cell Line | Pert Dose | Pert Time | Raw Score (GSE126848) | Normalized Score (GSE126848) | fdr_q_nlog10 (GSE126848) | Raw Score (GSE135251) | Normalized Score (GSE135251) | fdr_q_nlog10 (GSE135251) |
|---|---|---|---|---|---|---|---|---|---|---|
| 90890 | BRD-K15179513 | MCF10A | 1.11 uM | 6 h | -0.3 | -1.27 | 0.74 | 0.0 | 0.0 | 0.0 |
| 96882 | BRD-K15179513 | A375 | 3.33 uM | 24 h | -0.28 | -1.17 | 0.48 | 0.0 | 0.0 | 0.0 |
| 96958 | BRD-K15179513 | PC3 | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |