CMap Candidate Details

Structure:
CMap ID: C00719
Pert ID: BRD-A29082194
Compound Name: gitoxigenin
Targets: ATP1A1
MoA: ATPase inhibitor
SMILES: C[C@@]12CCC3C(CC[C@@H]4C[C@@H](O)CC[C@@]43C)[C@@]2(O)C[C@H](O)[C@@H]1C5=CC(=O)OC5
InchiKey: PVAMXWLZJKTXFW-YOUFMJPESA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
5150 BRD-A29082194 A375 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
5394 BRD-A29082194 HA1E 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
5510 BRD-A29082194 HCC515 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
5978 BRD-A29082194 HT29 10 uM 6 h 0.0 0.0 0.0 -0.25 -0.84 0.18
6238 BRD-A29082194 PC3 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
6458 BRD-A29082194 VCAP 10 uM 6 h 0.0 0.0 0.0 -0.29 -0.99 0.51
44479 BRD-A29082194 A549 10 uM 24 h 0.0 0.0 0.0 -0.37 -1.24 1.35
44756 BRD-A29082194 ASC 10 uM 24 h 0.17 0.73 0.0 -0.27 -0.9 0.29
45077 BRD-A29082194 HEPG2 10 uM 6 h 0.0 0.0 0.0 -0.27 -0.91 0.31
45608 BRD-A29082194 MCF??7.00 10 uM 24 h 0.26 1.09 0.22 -0.42 -1.43 15.35
45876 BRD-A29082194 NPC 10 uM 24 h 0.26 1.09 0.23 0.0 0.0 0.0
46189 BRD-A29082194 PHH 10 uM 24 h 0.0 0.0 0.0 -0.27 -0.91 0.31
46506 BRD-A29082194 SKB 10 uM 24 h 0.28 1.15 0.32 -0.29 -0.98 0.48
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).