CMap Candidate Details

Structure:
CMap ID: C00721
Pert ID: BRD-A29260609
Compound Name: acebutolol
Targets: ADRB1
MoA: Adrenergic receptor antagonist
SMILES: CCCC(=O)Nc1ccc(OCC(O)CNC(C)C)c(c1)C(C)=O
InchiKey: GOEMGAFJFRBGGG-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
50289 BRD-A29260609 HCC515 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
50981 BRD-A29260609 VCAP 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
51389 BRD-A29260609 PC3 10 uM 24 h 0.24 1.02 0.12 0.24 0.85 0.14
119953 BRD-A29260609 A375 3.33 uM 24 h 0.0 0.0 0.0 -0.22 -0.75 0.07
119995 BRD-A29260609 A549 10 uM 24 h -0.34 -1.4 1.15 -0.24 -0.81 0.13
120057 BRD-A29260609 HELA 1.11 uM 24 h 0.0 0.0 0.0 -0.24 -0.82 0.14
120112 BRD-A29260609 HT29 10 uM 24 h -0.18 -0.74 0.0 0.36 1.26 1.29
120154 BRD-A29260609 MCF??7.00 0.125 uM 24 h -0.3 -1.24 0.64 0.31 1.09 0.67
128816 BRD-A29260609 HA1E 0.74 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
128877 BRD-A29260609 YAPC 0.01 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).