CMap Candidate Details

Structure:
CMap ID: C07211
Pert ID: BRD-K15318909
Compound Name: PRIMA1
Targets: ACHE
MoA: TP53 inhibitor
SMILES: OCC1(CO)N2CCC(CC2)C1=O
InchiKey: RFBVBRVVOPAAFS-UHFFFAOYSA-N
Compound Aliases: PRIMA-1

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
8918 BRD-K15318909 A375 40 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
9183 BRD-K15318909 A549 40 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
9680 BRD-K15318909 H1299 40 uM 6 h 0.22 0.92 0.04 0.24 0.84 0.13
10035 BRD-K15318909 HA1E 40 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
10167 BRD-K15318909 HCC515 40 uM 24 h 0.2 0.85 0.01 0.0 0.0 0.0
10470 BRD-K15318909 HCT116 40 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
10743 BRD-K15318909 HEPG2 40 uM 6 h 0.0 0.0 0.0 -0.33 -1.1 0.87
11079 BRD-K15318909 HT29 40 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
11270 BRD-K15318909 MCF??7.00 40 uM 6 h 0.0 0.0 0.0 -0.25 -0.85 0.2
11432 BRD-K15318909 NCIH2073 40 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
11997 BRD-K15318909 NCIH596 40 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
12489 BRD-K15318909 PC3 40 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
12743 BRD-K15318909 SW480 40 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
13223 BRD-K15318909 U937 40 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
13453 BRD-K15318909 VCAP 40 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
96262 BRD-K15318909 U2OS 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).