CMap Candidate Details

Structure:
CMap ID: C00722
Pert ID: BRD-A29289453
Compound Name: PCA-4248
Targets: PTAFR
MoA: Platelet activating factor receptor antagonist
SMILES: COC(=O)C1=C(C)NC(C)=C(C1C)C(=O)OCCSc1ccccc1
InchiKey: DHCNAWNKZMNTIS-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
3095 BRD-A29289453 HCC515 10 uM 24 h -0.26 -1.07 0.28 0.0 0.0 0.0
3433 BRD-A29289453 PC3 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
3922 BRD-A29289453 VCAP 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
44757 BRD-A29289453 ASC 10 uM 24 h -0.23 -0.97 0.11 0.0 0.0 0.0
45078 BRD-A29289453 HEPG2 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
45877 BRD-A29289453 NPC 10 uM 24 h 0.2 0.84 0.0 0.28 0.99 0.42
46190 BRD-A29289453 PHH 10 uM 24 h 0.0 0.0 0.0 0.32 1.13 0.84
46507 BRD-A29289453 SKB 10 uM 24 h -0.32 -1.32 0.82 0.0 0.0 0.0
119950 BRD-A29289453 A375 0.125 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
119992 BRD-A29289453 A549 0.37 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
120028 BRD-A29289453 HA1E 10 uM 24 h 0.29 1.22 0.48 -0.35 -1.18 1.14
120055 BRD-A29289453 HELA 10 uM 24 h 0.0 0.0 0.0 -0.38 -1.29 1.53
120109 BRD-A29289453 HT29 1.11 uM 24 h 0.0 0.0 0.0 -0.25 -0.84 0.18
120151 BRD-A29289453 MCF??7.00 0.125 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
128874 BRD-A29289453 YAPC 0.03 uM 24 h 0.28 1.16 0.35 -0.28 -0.93 0.35
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).