CMap Candidate Details

Structure:
CMap ID: C07233
Pert ID: BRD-K15402119
Compound Name: huperzine-a
Targets: ACHE
MoA: Glutamate receptor antagonist; Acetylcholinesterase inhibitor
SMILES: CC=C1/[C@H]2Cc3[nH]c(=O)ccc3[C@]1(N)CC(C)=C2
InchiKey: ZRJBHWIHUMBLCN-JRYCNTDSSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
25637 BRD-K15402119 A375 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
25909 BRD-K15402119 A549 10 uM 24 h 0.0 0.0 0.0 -0.28 -0.93 0.34
26281 BRD-K15402119 ASC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
26618 BRD-K15402119 HA1E 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
26930 BRD-K15402119 HCC515 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
27241 BRD-K15402119 HT29 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
27678 BRD-K15402119 MCF??7.00 10 uM 6 h 0.0 0.0 0.0 0.23 0.83 0.11
27864 BRD-K15402119 NEU 10 uM 24 h 0.0 0.0 0.0 -0.4 -1.35 2.01
28173 BRD-K15402119 NPC 10 uM 24 h 0.22 0.92 0.04 0.22 0.77 0.06
28602 BRD-K15402119 PC3 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
29132 BRD-K15402119 SKB 10 uM 24 h 0.0 0.0 0.0 0.42 1.48 2.25
29436 BRD-K15402119 VCAP 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
95970 BRD-K15402119 PHH 1.11 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).