CMap Candidate Details

Structure:
CMap ID: C07252
Pert ID: BRD-K15453459
Compound Name: BRD-K15453459
Targets: --
MoA: --
SMILES: COc1cccc(CNC(=O)c2cc3CN([C@@H](CCO)c3c(n2)-c2cccc(c2)-c2ccc(cc2)C#N)[S@@](=O)C(C)(C)C)c1
InchiKey: PAVPSZKVOXNNCU-JCFUSDQVSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
59668 BRD-K15453459 VCAP 4 uM 24 h 0.0 0.0 0.0 -0.28 -0.95 0.42
68034 BRD-K15453459 A549 4 uM 24 h -0.25 -1.06 0.24 0.28 0.99 0.39
85746 BRD-K15453459 A375 4 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
85923 BRD-K15453459 HA1E 4 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
86030 BRD-K15453459 HCC515 20 uM 24 h -0.32 -1.33 0.89 -0.32 -1.08 0.81
86138 BRD-K15453459 HEPG2 20 uM 24 h -0.25 -1.02 0.18 -0.32 -1.09 0.84
86243 BRD-K15453459 HT29 20 uM 24 h -0.28 -1.15 0.44 0.0 0.0 0.0
86329 BRD-K15453459 MCF??7.00 20 uM 24 h 0.0 0.0 0.0 -0.33 -1.13 0.98
86415 BRD-K15453459 PC3 20 uM 24 h 0.0 0.0 0.0 0.22 0.78 0.06
110118 BRD-K15453459 U2OS 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).