CMap Candidate Details

Structure:
CMap ID: C07268
Pert ID: BRD-K15502390
Compound Name: nevirapine
Targets: CYP1A2; CYP2A6; CYP2B6; CYP2C9; CYP2D6; CYP3A4; CYP3A5
MoA: Reverse transcriptase inhibitor
SMILES: Cc1ccnc2c1NC(=O)c1cccnc1N2C1CC1
InchiKey: NQDJXKOVJZTUJA-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
25492 BRD-K15502390 VCAP 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
96641 BRD-K15502390 A375 3.33 uM 24 h -0.3 -1.23 0.63 0.32 1.13 0.82
120259 BRD-K15502390 A549 0.37 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
120391 BRD-K15502390 MCF??7.00 10 uM 24 h -0.23 -0.94 0.08 0.0 0.0 0.0
120452 BRD-K15502390 YAPC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
128900 BRD-K15502390 HA1E 0.03 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
128916 BRD-K15502390 HELA 0.74 uM 24 h -0.24 -0.99 0.13 -0.36 -1.21 1.24
128933 BRD-K15502390 HT29 0.08 uM 24 h 0.26 1.09 0.23 0.0 0.0 0.0
128966 BRD-K15502390 PC3 0.08 uM 24 h 0.0 0.0 0.0 0.33 1.16 0.9
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).