CMap Candidate Details

Structure:
CMap ID: C00727
Pert ID: BRD-A29426959
Compound Name: carbinoxamine
Targets: HRH1
MoA: Histamine receptor antagonist; L-type calcium channel blocker
SMILES: CN(C)CCOC(c1ccc(Cl)cc1)c1ccccn1
InchiKey: OJFSXZCBGQGRNV-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
5151 BRD-A29426959 A375 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
5260 BRD-A29426959 HA1E 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
5720 BRD-A29426959 HCC515 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
5834 BRD-A29426959 HEPG2 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
6067 BRD-A29426959 MCF??7.00 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
6239 BRD-A29426959 PC3 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
6351 BRD-A29426959 VCAP 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
37469 BRD-A29426959 ASC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
37993 BRD-A29426959 HT29 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
38319 BRD-A29426959 NPC 10 uM 24 h 0.0 0.0 0.0 -0.22 -0.74 0.06
38618 BRD-A29426959 PHH 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
49940 BRD-A29426959 A549 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).