CMap Candidate Details

Structure:
CMap ID: C07273
Pert ID: BRD-K15507868
Compound Name: tesaglitazar
Targets: PPARA; PPARG
MoA: Insulin sensitizer; PPAR receptor agonist
SMILES: CCO[C@@H](Cc1ccc(OCCc2ccc(OS(C)(=O)=O)cc2)cc1)C(O)=O
InchiKey: CXGTZJYQWSUFET-IBGZPJMESA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
120228 BRD-K15507868 A375 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
120262 BRD-K15507868 A549 1.11 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
120302 BRD-K15507868 HA1E 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
120334 BRD-K15507868 HELA 1.11 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
120393 BRD-K15507868 MCF??7.00 0.37 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
120455 BRD-K15507868 YAPC 10 uM 24 h 0.0 0.0 0.0 0.26 0.92 0.25
128935 BRD-K15507868 HT29 2.22 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
128968 BRD-K15507868 PC3 0.74 uM 24 h 0.22 0.9 0.03 0.3 1.07 0.63
136439 BRD-K15507868 SHSY5Y 0.37 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).