CMap Candidate Details

Structure:
CMap ID: C00729
Pert ID: BRD-A29485665
Compound Name: bicalutamide
Targets: AR
MoA: Androgen receptor antagonist
SMILES: CC(O)(CS(=O)(=O)c1ccc(F)cc1)C(=O)Nc1ccc(C#N)c(c1)C(F)(F)F
InchiKey: LKJPYSCBVHEWIU-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
4289 BRD-A29485665 HCC515 10 uM 24 h 0.0 0.0 0.0 0.24 0.85 0.15
24522 BRD-A29485665 A549 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
37471 BRD-A29485665 ASC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
38321 BRD-A29485665 NPC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
38620 BRD-A29485665 PHH 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
38840 BRD-A29485665 SKB 10 uM 24 h 0.0 0.0 0.0 0.22 0.77 0.06
88413 BRD-A29485665 VCAP 2.22 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
91148 BRD-A29485665 HUH7 8 uM 72 h 0.0 0.0 0.0 0.0 0.0 0.0
121890 BRD-A29485665 A375 3.33 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
122005 BRD-A29485665 HT29 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
122042 BRD-A29485665 HUVEC 3.33 uM 24 h 0.0 0.0 0.0 -0.23 -0.78 0.1
122105 BRD-A29485665 MCF??7.00 1.11 uM 24 h 0.0 0.0 0.0 -0.39 -1.33 1.71
122161 BRD-A29485665 PC3 1.11 uM 24 h -0.35 -1.48 1.43 0.0 0.0 0.0
122216 BRD-A29485665 YAPC 0.37 uM 24 h 0.0 0.0 0.0 -0.23 -0.78 0.09
130222 BRD-A29485665 HA1E 0.74 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
130254 BRD-A29485665 HEK293 2.22 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
130284 BRD-A29485665 HELA 0.74 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
130343 BRD-A29485665 JURKAT 0.25 uM 24 h -0.26 -1.09 0.31 0.0 0.0 0.0
130393 BRD-A29485665 MCF10A 2.22 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
130447 BRD-A29485665 MDAMB231 0.25 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
130493 BRD-A29485665 THP1 0.74 uM 24 h 0.0 0.0 0.0 0.25 0.9 0.22
136430 BRD-A29485665 SHSY5Y 0.125 uM 24 h 0.25 1.04 0.15 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).