CMap Candidate Details

Structure:
CMap ID: C07291
Pert ID: BRD-K15567136
Compound Name: papaverine
Targets: PDE10A
MoA: Phosphodiesterase inhibitor
SMILES: COc1ccc(Cc2nccc3cc(OC)c(OC)cc23)cc1OC
InchiKey: XQYZDYMELSJDRZ-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
2986 BRD-K15567136 HA1E 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
3146 BRD-K15567136 HCC515 10 uM 24 h -0.21 -0.86 0.02 0.0 0.0 0.0
3729 BRD-K15567136 VCAP 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
44872 BRD-K15567136 ASC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
45176 BRD-K15567136 HEPG2 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
45658 BRD-K15567136 MCF??7.00 10 uM 24 h 0.0 0.0 0.0 -0.32 -1.08 0.79
45989 BRD-K15567136 NPC 10 uM 24 h 0.19 0.77 0.0 -0.26 -0.87 0.22
46307 BRD-K15567136 PHH 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
46622 BRD-K15567136 SKB 10 uM 24 h 0.0 0.0 0.0 0.37 1.3 1.49
96989 BRD-K15567136 A375 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
97067 BRD-K15567136 PC3 10 uM 24 h 0.0 0.0 0.0 -0.24 -0.81 0.14
100133 BRD-K15567136 U2OS 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
120260 BRD-K15567136 A549 10 uM 24 h 0.2 0.82 0.0 -0.36 -1.21 1.24
120332 BRD-K15567136 HELA 10 uM 24 h 0.0 0.0 0.0 0.3 1.06 0.58
120453 BRD-K15567136 YAPC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
128934 BRD-K15567136 HT29 0.74 uM 24 h 0.0 0.0 0.0 -0.33 -1.1 0.86
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).