CMap Candidate Details
Structure:
| CMap ID: | C07293 |
| Pert ID: | BRD-K15574380 |
| Compound Name: | capecitabine |
| Targets: | TYMS |
| MoA: | DNA synthesis inhibitor; Thymidylate synthase inhibitor |
| SMILES: | CCCCCOC(=O)Nc1nc(=O)n(cc1F)[C@@H]1O[C@H](C)[C@@H](O)[C@@H]1O |
| InchiKey: | GAGWJHPBXLXJQN-GMTLJSCSSA-N |
| Compound Aliases: | -- |
| Score ID | Pert ID | Cell Line | Pert Dose | Pert Time | Raw Score (GSE126848) | Normalized Score (GSE126848) | fdr_q_nlog10 (GSE126848) | Raw Score (GSE135251) | Normalized Score (GSE135251) | fdr_q_nlog10 (GSE135251) |
|---|---|---|---|---|---|---|---|---|---|---|
| 95484 | BRD-K15574380 | A549 | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | -0.32 | -1.06 | 0.74 |
| 95572 | BRD-K15574380 | MCF??7.00 | 10 uM | 48 h | 0.26 | 1.1 | 0.24 | 0.0 | 0.0 | 0.0 |
| 95665 | BRD-K15574380 | U2OS | 0.12 uM | 48 h | 0.0 | 0.0 | 0.0 | -0.4 | -1.35 | 2.02 |