CMap Candidate Details

Structure:
CMap ID: C07296
Pert ID: BRD-K15588452
Compound Name: R-96544
Targets: HTR2A
MoA: Serotonin receptor antagonist
SMILES: COc1cccc(CCc2ccccc2OCC[C@@H]2C[C@@H](O)CN2C)c1
InchiKey: AFZLABYDOCWQBQ-WOJBJXKFSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
4069 BRD-K15588452 HA1E 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
4376 BRD-K15588452 HCC515 10 uM 24 h 0.0 0.0 0.0 0.36 1.27 1.34
4784 BRD-K15588452 PC3 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
4901 BRD-K15588452 VCAP 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
44318 BRD-K15588452 A375 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
44532 BRD-K15588452 A549 10 uM 24 h 0.0 0.0 0.0 -0.29 -0.99 0.51
44873 BRD-K15588452 ASC 10 uM 24 h -0.3 -1.27 0.74 0.0 0.0 0.0
45177 BRD-K15588452 HEPG2 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
45445 BRD-K15588452 HT29 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
45781 BRD-K15588452 MCF??7.00 10 uM 6 h 0.25 1.03 0.13 0.0 0.0 0.0
45990 BRD-K15588452 NPC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
46308 BRD-K15588452 PHH 10 uM 24 h 0.0 0.0 0.0 -0.27 -0.9 0.28
46623 BRD-K15588452 SKB 10 uM 24 h -0.22 -0.91 0.05 0.0 0.0 0.0
100135 BRD-K15588452 U2OS 10 uM 6 h 0.0 0.0 0.0 0.31 1.08 0.66
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).