CMap Candidate Details

Structure:
CMap ID: C00737
Pert ID: BRD-A29734509
Compound Name: disopyramide
Targets: SCN5A
MoA: Sodium channel blocker
SMILES: CC(C)N(CCC(C(N)=O)(c1ccccc1)c1ccccn1)C(C)C
InchiKey: UVTNFZQICZKOEM-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
5511 BRD-A29734509 HCC515 10 uM 24 h 0.0 0.0 0.0 -0.27 -0.9 0.29
6459 BRD-A29734509 VCAP 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
42193 BRD-A29734509 ASC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
42538 BRD-A29734509 HEPG2 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
43394 BRD-A29734509 NPC 10 uM 24 h 0.0 0.0 0.0 -0.35 -1.17 1.13
43708 BRD-A29734509 PHH 10 uM 24 h 0.0 0.0 0.0 -0.28 -0.95 0.41
51205 BRD-A29734509 MCF??7.00 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
119956 BRD-A29734509 A375 0.125 uM 24 h 0.0 0.0 0.0 0.26 0.94 0.28
120000 BRD-A29734509 A549 10 uM 24 h 0.38 1.59 1.52 0.27 0.94 0.3
120061 BRD-A29734509 HELA 0.125 uM 24 h 0.0 0.0 0.0 -0.3 -1.02 0.6
120116 BRD-A29734509 HT29 3.33 uM 24 h -0.2 -0.84 0.01 -0.36 -1.2 1.16
120193 BRD-A29734509 PC3 0.04 uM 24 h 0.0 0.0 0.0 0.26 0.92 0.25
128819 BRD-A29734509 HA1E 0.01 uM 24 h 0.0 0.0 0.0 -0.24 -0.82 0.15
128881 BRD-A29734509 YAPC 0.01 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).