CMap Candidate Details

Structure:
CMap ID: C07437
Pert ID: BRD-K16037980
Compound Name: Z160
Targets: CACNA1B
MoA: N-type calcium channel blocker
SMILES: O=C(CC(c1ccccc1)c1ccccc1)N1CCN(CC1)C(c1ccccc1)c1ccccc1
InchiKey: VCPMZDWBEWTGNW-UHFFFAOYSA-N
Compound Aliases: Z-160

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
120231 BRD-K16037980 A375 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
120265 BRD-K16037980 A549 10 uM 24 h 0.23 0.95 0.06 0.0 0.0 0.0
120304 BRD-K16037980 HA1E 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
120373 BRD-K16037980 HT29 10 uM 24 h -0.19 -0.78 0.0 0.24 0.86 0.15
120395 BRD-K16037980 MCF??7.00 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
120429 BRD-K16037980 PC3 10 uM 24 h 0.31 1.31 0.73 0.0 0.0 0.0
120459 BRD-K16037980 YAPC 1.11 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
128917 BRD-K16037980 HELA 0.74 uM 24 h 0.0 0.0 0.0 0.2 0.71 0.02
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).