CMap Candidate Details

Structure:
CMap ID: C07452
Pert ID: BRD-K16077845
Compound Name: fentiazac
Targets: PTGS1; PTGS2
MoA: Cyclooxygenase inhibitor
SMILES: OC(=O)Cc1sc(nc1-c1ccc(Cl)cc1)-c1ccccc1
InchiKey: JIEKMACRVQTPRC-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
51592 BRD-K16077845 MCF??7.00 10 uM 24 h 0.0 0.0 0.0 -0.3 -1.01 0.58
51804 BRD-K16077845 PC3 10 uM 24 h 0.0 0.0 0.0 0.26 0.92 0.24
91080 BRD-K16077845 HUH7 10 uM 72 h 0.0 0.0 0.0 0.21 0.74 0.04
120233 BRD-K16077845 A375 10 uM 24 h 0.0 0.0 0.0 -0.51 -1.73 15.65
120268 BRD-K16077845 A549 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
120306 BRD-K16077845 HA1E 10 uM 24 h 0.0 0.0 0.0 -0.23 -0.79 0.1
120337 BRD-K16077845 HELA 3.33 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
120374 BRD-K16077845 HT29 10 uM 24 h 0.0 0.0 0.0 -0.25 -0.85 0.19
120462 BRD-K16077845 YAPC 3.33 uM 24 h 0.0 0.0 0.0 -0.31 -1.05 0.72
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).