CMap Candidate Details

Structure:
CMap ID: C00751
Pert ID: BRD-A30435184
Compound Name: metergoline
Targets: HTR1A; HTR2A
MoA: Serotonin receptor antagonist; Dopamine receptor agonist
SMILES: CN1CC(CNC(=O)OCc2ccccc2)CC3C1Cc4cn(C)c5cccc3c45
InchiKey: WZHJKEUHNJHDLS-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
6629 BRD-A30435184 A375 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
7064 BRD-A30435184 A549 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
7214 BRD-A30435184 HA1E 10 uM 24 h 0.2 0.84 0.0 0.35 1.23 1.24
7757 BRD-A30435184 HT29 10 uM 24 h 0.0 0.0 0.0 0.33 1.15 0.9
8208 BRD-A30435184 MCF??7.00 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
8299 BRD-A30435184 PC3 10 uM 24 h -0.16 -0.66 0.0 0.27 0.97 0.36
8562 BRD-A30435184 VCAP 10 uM 24 h 0.0 0.0 0.0 0.36 1.26 1.29
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).