CMap Candidate Details

Structure:
CMap ID: C07589
Pert ID: BRD-K16485616
Compound Name: mocetinostat
Targets: HDAC1; HDAC2; HDAC11; HDAC3
MoA: HDAC inhibitor
SMILES: Nc1ccccc1NC(=O)c1ccc(CNc2nccc(n2)-c2cccnc2)cc1
InchiKey: HRNLUBSXIHFDHP-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
33687 BRD-K16485616 A375 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
33892 BRD-K16485616 A549 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
34839 BRD-K16485616 HEPG2 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
35104 BRD-K16485616 HT29 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
35300 BRD-K16485616 MCF??7.00 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
36213 BRD-K16485616 PHH 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
36508 BRD-K16485616 SKB 10 uM 24 h 0.16 0.65 0.0 0.0 0.0 0.0
36951 BRD-K16485616 VCAP 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
93684 BRD-K16485616 ASC 3.33 uM 24 h 0.22 0.92 0.04 0.0 0.0 0.0
93716 BRD-K16485616 CD34 10 uM 24 h 0.24 1.01 0.11 0.0 0.0 0.0
93759 BRD-K16485616 HA1E 0.04 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
93794 BRD-K16485616 HCC515 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
93843 BRD-K16485616 HEK293 3.33 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
93887 BRD-K16485616 HELA 0.04 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
93990 BRD-K16485616 HUVEC 10 uM 24 h 0.24 1.02 0.12 -0.32 -1.06 0.74
94027 BRD-K16485616 JURKAT 3.33 uM 24 h 0.21 0.89 0.02 0.0 0.0 0.0
94106 BRD-K16485616 NEU 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
94139 BRD-K16485616 NPC 0.12 uM 24 h 0.0 0.0 0.0 -0.26 -0.89 0.27
94193 BRD-K16485616 PC3 1.11 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
94239 BRD-K16485616 SHSY5Y 0.12 uM 24 h 0.0 0.0 0.0 -0.25 -0.84 0.18
94291 BRD-K16485616 SKL 3.33 uM 24 h -0.25 -1.06 0.26 0.0 0.0 0.0
94338 BRD-K16485616 THP1 0.12 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
94381 BRD-K16485616 YAPC 10 uM 24 h 0.0 0.0 0.0 -0.29 -0.97 0.46
100146 BRD-K16485616 U2OS 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).