CMap Candidate Details

Structure:
CMap ID: C07597
Pert ID: BRD-K16508793
Compound Name: diazepam
Targets: GABRA1; GABRA2; GABRA3; GABRA4; GABRA5; GABRA6; GABRB1; GABRB2; GABRB3; GABRD; GABRE; GABRG1; GABRG2; GABRG3; GABRP; GABRQ
MoA: Benzodiazepine receptor agonist
SMILES: CN1c2ccc(Cl)cc2C(=NCC1=O)c1ccccc1
InchiKey: AAOVKJBEBIDNHE-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
2091 BRD-K16508793 HCC515 10 uM 6 h 0.0 0.0 0.0 -0.2 -0.68 0.02
2619 BRD-K16508793 VCAP 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
97119 BRD-K16508793 A375 10 uM 24 h -0.25 -1.02 0.19 -0.24 -0.81 0.13
97184 BRD-K16508793 PC3 10 uM 24 h 0.0 0.0 0.0 -0.25 -0.83 0.16
100147 BRD-K16508793 U2OS 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
120272 BRD-K16508793 A549 0.125 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
120310 BRD-K16508793 HA1E 3.33 uM 24 h 0.23 0.95 0.06 0.24 0.87 0.17
120338 BRD-K16508793 HELA 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
120401 BRD-K16508793 MCF??7.00 0.125 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
120467 BRD-K16508793 YAPC 3.33 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
128944 BRD-K16508793 HT29 0.74 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).