CMap Candidate Details

Structure:
CMap ID: C07608
Pert ID: BRD-K16541732
Compound Name: BRD-K16541732
Targets: --
MoA: --
SMILES: COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CC(=O)N(CCO)Cc4ccccc4)C(=O)N(Cc5ccc(cc5)N6CCOC6=O)c7ccccc73
InchiKey: CABDNGHWHLNZPZ-ROOVVSHOSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
29797 BRD-K16541732 A375 10 uM 6 h 0.22 0.9 0.02 0.0 0.0 0.0
30036 BRD-K16541732 A549 10 uM 24 h 0.0 0.0 0.0 -0.29 -0.98 0.48
30379 BRD-K16541732 ASC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
30698 BRD-K16541732 HA1E 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
30981 BRD-K16541732 HCC515 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
31286 BRD-K16541732 HEPG2 10 uM 6 h -0.29 -1.2 0.55 -0.45 -1.5 15.35
31694 BRD-K16541732 HT29 10 uM 6 h -0.18 -0.76 0.0 0.0 0.0 0.0
31841 BRD-K16541732 MCF??7.00 10 uM 24 h 0.0 0.0 0.0 -0.34 -1.16 1.09
32145 BRD-K16541732 NEU 10 uM 24 h 0.0 0.0 0.0 -0.28 -0.96 0.42
32368 BRD-K16541732 NPC 10 uM 24 h 0.0 0.0 0.0 -0.28 -0.95 0.41
32615 BRD-K16541732 PC3 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
32961 BRD-K16541732 SKB 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
33251 BRD-K16541732 VCAP 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).