CMap Candidate Details

Structure:
CMap ID: C07615
Pert ID: BRD-K16554956
Compound Name: PTB1
Targets: PTPN1
MoA: AMPK activator
SMILES: OP(O)(=O)C(F)(F)c1cc2cc(ccc2cc1Br)C#N
InchiKey: BWJOQFMMTKEZGA-UHFFFAOYSA-N
Compound Aliases: PTB-1

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
9185 BRD-K16554956 A549 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
9684 BRD-K16554956 H1299 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
10037 BRD-K16554956 HA1E 10 uM 6 h 0.0 0.0 0.0 0.31 1.09 0.67
10297 BRD-K16554956 HCC515 10 uM 6 h 0.25 1.03 0.13 0.0 0.0 0.0
10473 BRD-K16554956 HCT116 10 uM 6 h 0.3 1.24 0.52 0.0 0.0 0.0
10746 BRD-K16554956 HEPG2 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
11078 BRD-K16554956 HT29 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
11174 BRD-K16554956 MCF??7.00 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
11724 BRD-K16554956 NCIH508 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
12000 BRD-K16554956 NCIH596 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
12745 BRD-K16554956 SW480 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
13226 BRD-K16554956 U937 10 uM 6 h 0.0 0.0 0.0 -0.29 -0.96 0.44
13592 BRD-K16554956 VCAP 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
96048 BRD-K16554956 PHH 1.11 uM 24 h 0.0 0.0 0.0 -0.22 -0.74 0.05
96449 BRD-K16554956 A375 3.33 uM 24 h 0.23 0.97 0.08 0.39 1.4 2.18
96517 BRD-K16554956 PC3 3.33 uM 24 h 0.0 0.0 0.0 -0.23 -0.76 0.07
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).