CMap Candidate Details

Structure:
CMap ID: C07644
Pert ID: BRD-K16664969
Compound Name: GTP-14564
Targets: FLT3
MoA: FLT3 inhibitor; Tyrosine kinase inhibitor
SMILES: c1ccc(cc1)-c1n[nH]c2c1oc1ccccc21
InchiKey: DZQLVVLATXPWBK-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
2843 BRD-K16664969 HA1E 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
3337 BRD-K16664969 HCC515 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
3733 BRD-K16664969 VCAP 10 uM 24 h -0.27 -1.13 0.4 0.0 0.0 0.0
39303 BRD-K16664969 A549 10 uM 24 h -0.26 -1.06 0.26 -0.26 -0.88 0.26
39636 BRD-K16664969 ASC 10 uM 24 h -0.21 -0.89 0.04 0.0 0.0 0.0
39952 BRD-K16664969 HEPG2 10 uM 6 h -0.32 -1.33 0.91 -0.31 -1.06 0.73
40233 BRD-K16664969 HT29 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
40455 BRD-K16664969 MCF??7.00 10 uM 24 h 0.2 0.84 0.0 -0.33 -1.1 0.86
41060 BRD-K16664969 NPC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
41389 BRD-K16664969 SKB 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
97167 BRD-K16664969 A375 10 uM 24 h 0.27 1.13 0.28 0.22 0.77 0.06
97232 BRD-K16664969 PC3 10 uM 24 h -0.2 -0.85 0.01 0.25 0.87 0.17
100152 BRD-K16664969 U2OS 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).