CMap Candidate Details

Structure:
CMap ID: C00765
Pert ID: BRD-A30977374
Compound Name: nifedipine
Targets: CACNA1C; CACNA1D; CACNA1F; CACNA1S; CACNA2D1
MoA: Calcium channel blocker
SMILES: COC(=O)C1C(C(=C(C)N=C1C)C(=O)OC)c2ccccc2[N+](=O)[O-]
InchiKey: OSUCQKNXQBPLDG-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
24377 BRD-A30977374 A375 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
24642 BRD-A30977374 A549 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
24715 BRD-A30977374 HA1E 10 uM 6 h 0.0 0.0 0.0 0.24 0.85 0.14
24838 BRD-A30977374 HT29 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
25064 BRD-A30977374 MCF??7.00 10 uM 6 h 0.26 1.07 0.2 0.0 0.0 0.0
25215 BRD-A30977374 PC3 10 uM 6 h 0.0 0.0 0.0 0.37 1.31 1.59
25285 BRD-A30977374 VCAP 10 uM 24 h 0.0 0.0 0.0 0.28 0.99 0.41
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).