CMap Candidate Details

Structure:
CMap ID: C07671
Pert ID: BRD-K16732600
Compound Name: MK-0893
Targets: GCGR
MoA: Glucagon receptor antagonist
SMILES: COc1ccc2cc(ccc2c1)-c1cc(nn1[C@@H](C)c1ccc(cc1)C(=O)NCCC(O)=O)-c1cc(Cl)cc(Cl)c1
InchiKey: DNTVJEMGHBIUMW-IBGZPJMESA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
120240 BRD-K16732600 A375 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
120276 BRD-K16732600 A549 3.33 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
120314 BRD-K16732600 HA1E 1.11 uM 24 h 0.0 0.0 0.0 -0.26 -0.88 0.25
120340 BRD-K16732600 HELA 10 uM 24 h 0.0 0.0 0.0 0.3 1.05 0.58
120375 BRD-K16732600 HT29 10 uM 24 h 0.0 0.0 0.0 0.38 1.33 1.72
120404 BRD-K16732600 MCF??7.00 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
120434 BRD-K16732600 PC3 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
120472 BRD-K16732600 YAPC 0.04 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).