CMap Candidate Details

Structure:
CMap ID: C00772
Pert ID: BRD-A31159102
Compound Name: fluoxetine
Targets: SLC6A4
MoA: Selective serotonin reuptake inhibitor
SMILES: CNCCC(Oc1ccc(cc1)C(F)(F)F)c1ccccc1
InchiKey: RTHCYVBBDHJXIQ-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
1466 BRD-A31159102 NPC 25 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
7521 BRD-A31159102 HCC515 10 uM 6 h 0.0 0.0 0.0 0.35 1.24 1.24
20192 BRD-A31159102 HEPG2 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
21680 BRD-A31159102 VCAP 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
91337 BRD-A31159102 HUH7 10 uM 72 h 0.0 0.0 0.0 0.0 0.0 0.0
95476 BRD-A31159102 U2OS 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
98289 BRD-A31159102 NEU 10 uM 24 h 0.0 0.0 0.0 0.25 0.89 0.21
120508 BRD-A31159102 A375 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
120540 BRD-A31159102 A549 10 uM 24 h 0.3 1.24 0.51 0.38 1.34 1.72
120586 BRD-A31159102 HA1E 10 uM 24 h 0.24 0.99 0.1 0.4 1.43 2.2
120612 BRD-A31159102 HELA 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
120641 BRD-A31159102 HT29 10 uM 24 h -0.19 -0.78 0.0 0.0 0.0 0.0
120691 BRD-A31159102 JURKAT 0.37 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
120745 BRD-A31159102 MCF??7.00 10 uM 24 h 0.0 0.0 0.0 -0.28 -0.94 0.36
120765 BRD-A31159102 PC3 10 uM 24 h 0.0 0.0 0.0 0.21 0.74 0.03
120797 BRD-A31159102 YAPC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).